Physiological Systems Modeling, Simulation and Control

Code 3.2.3326.9
Semester 9th
Flow I - Bioengineering
Category Obligatory (main flow)
Credits 6
Class Hours - Lab Hours 2 - 2
Lecturers Konstantina Nikita
Links Helios, Course's Website
Web Platform Class 1: Microsoft Teams


This course introduces students to computer-based mathematical modeling techniques to evaluate the structure and function of physiological systems through the analysis of their dynamic behavior. It includes the following topics: Applications of mathematical & computer physiological models; Fundamental principles, processes and tools in model development; Analysis and synthesis of dynamic models; Compartmental models of physiological systems; Neural Networks for physiological systems modeling and control; Identification of physiological systems; Cardiovascular system physiology, modeling and control; Modeling of glucose-insulin metabolic system; Introduction to bioinformatics and computational biology; Modeling of tumor growth and response to radiotherapy. The course includes laboratory exercises on bioinformatics and computational biology, modeling of tumor growth and response to radiotherapy, modeling of glucose-insulin metabolic system, computational neuroscience, emphasizing the exploitation of the corresponding tools towards improving both diagnosis and disease treatment.